Yuzhe (Cathy) Du
|Name||Yuzhe (Cathy) Du|
|Title||Assistant Professor (fixed term)|
Yuzhe (Cathy) Du has long-standing interests in insect toxicology and neurobiology. She joined Dr. Dong’s laboratory in the Department of Entomology at Michigan State University as a postdoctoral associate in 2003 and was promoted to a fix-termed Assistant Professor in 2010. Over the past 10 years, she has been working on NIH-funded projects to understand the mechanisms of action and resistance of sodium-channel-targeted neurotoxins and insecticides, including pyrethroids and sodium channel blocker insecticides (SCBIs).
One of Cathy’s major accomplishments is the successful expression of Aedes aegypti and varroa mite sodium channels in Xenopus oocytes in collaboration with Yoshiko Nomura, a molecular biologist in the lab. These technical breakthroughs allowed them to discover the unique pharmacology of varroa mite sodium channel, the first non-insect invertebrate sodium channel, and identify the second pyrethroid receptor site on the mosquito sodium channel.
Cathy is proficient in all the electrophysiology experimental techniques, including two-electrode voltage clamp, micro-patch, and patch clamp techniques.